Aplastic anemia treatment
Aplastic anemia is a blood disorder caused by faulty or damaged bone marrow. Red blood cells, White blood cells, and platelets are produced in bone marrow. When the bone marrow is unable to produce adequate blood cells (RBCs, WBCs, and platelets) the affected person is diagnosed as a patient of Aplastic Anemia. A patient with Aplastic anemia will suffer from frequent infections due to a low number of white blood cells, prone to bruising and easy and uncontrolled bleeds because of low platelets, and generalized malice and fatigue due to low red blood cells. The curative treatment for Aplastic anemia is an allogeneic hematopoietic stem cell transplant (HSCT). CMCS Health, a leading medical tourism assistance company offers low-cost curative Aplastic anemia treatment in India with the best bone marrow transplant doctors at top hospitals.
Aplastic anemia treatment in India
Aplastic anemia is a blood disorder that affects the production of erythrocytes (red blood cells), Lymphocytes (white blood cells), and thrombocytes (platelets). All the blood cells (RBCs, WBCs, and platelets) are produced in the bone marrow. When the bone marrow is damaged or faulty it can not produce adequate numbers of blood cells. Low red blood cell count in Aplastic anemia patients causes generalized malice and tiredness, low white blood cell counts cause frequent infections in Aplastic anemia patients, and low platelet counts cause easy bruising and bleeding. Aplastic anemia treatments depend on the severity of the disease and associated symptoms. Aplastic anemia can affect people of any age. It can be chronic (starts slowly and worsens over some time) or acute (sudden). Aplastic anemia can be mild, moderate, or severe. The best Aplastic anemia treatment doctors in India offer low-cost allogeneic bone marrow transplants as curative Aplastic anemia treatment in India.
Symptomatic Relief - Aplastic Anemia treatment
Aplastic anemia patients are given the following medicinal treatments. However, these Aplastic anemia treatment provides symptomatic relief to patients. These treatments do not cure Aplastic anemia.
Frequent blood transfusions
Aplastic anemia patients are given frequent blood transfusions to treat the symptoms. Frequent blood transfusions do not cure aplastic anemia, moreover, these frequent blood transfusions may make the patient suffer from iron overload and will need iron chelation therapy to avoid the complications of iron overload. Frequent blood transfusions also develop antibodies in Aplastic anemia patients and gradually the blood transfusions may not be able to relieve the symptoms.
Antibiotics and antiviral therapies
Because of the production of low lymphocytes (white blood cells), Aplastic anemia patients are prone to frequent infections. Prophylactic antibiotics and antiviral therapies help to relieve the symptoms in Aplastic anemia patients.
Immunosuppression therapy
Immunosuppression medications are prescribed for Aplastic anemia patients where the body's immunity is damaging the bone marrow and subsequent production of blood cells. Cyclosporins and anti-thymocyte globulin (ATG) injections are used for the treatment of Aplastic anemia. Other immunosuppressive medications like steroids (methylprednisolone) are also used in conjunction with cyclosporins and ATG injections. By suppressing the immunity the best Aplastic anemia treatment doctors in India, give time for the damaged bone marrow to recover and commence the production of blood cells. However, immunosuppression may make Aplastic anemia patients more vulnerable to infections. There is a strong possibility that Aplastic anemia may return once the treatment is over.
Bone marrow stimulant medications
Certain medications like granulocyte-colony stimulating factor injections may also be used in conjunction with immunosuppressive medications and erythropoiesis factors to stimulate the bone marrow in producing more blood cells.
Curative Aplastic Anemia Treatment in India
Best Aplastic anemia treatment doctors in India are providing curative Aplastic anemia treatment in India with allogeneic hematopoietic stem cell transplant (HSCT) or bone marrow transplant (BMT). Unlike the symptomatic relief treatments which may not be long-lasting and the patients may have anemia once the treatment is over, the allogeneic bone marrow transplant is a definite and documented cure for Aplastic Anemia. Best Aplastic anemia doctors in India offer low-cost yet the best success rates for allogeneic bone marrow transplants for Aplastic anemia treatment in India.
CMCS Health The best medical tourism assistance company has successfully coordinated Aplastic anemia treatment in India for Mr. Ezzat Ullah Qeenat from Afghanistan. We did HLA matching of Mr. Ezzatullah with two of his brothers and one sister by getting buccal swabs from Afghanistan. We did high-resolution HLA match tests in Indian laboratories. Mr. Ezzat was lucky that one of the Brother's HLA matches was 100% identical in the tests. We Invited Mr. Ezzat to India with his HLA identical brother for an allogeneic bone marrow transplant for his Aplastic anemia treatment in India. The allogeneic bone marrow transplant was done at Artemis Hospital, Gurugram India under one of the best Aplastic anemia treatment doctors in India, Dr. Pawan Kumar Singh.
After almost 7 years of successful Aplastic anemia treatment in India (allogeneic bone marrow transplant) Mr. Ezzatullah is free from Aplastic anemia and is living a normal healthy life. CMCS Health, one of the best medical tourism companies has coordinated successful allogeneic bone marrow transplants for Aplastic anemia treatment in India for many international patients.
Video - A successful Aplastic anemia treatment in India for an Afghan patient.
The success rate of Aplastic anemia treatment in India
The success rates of Aplastic anemia treatment in India depends on many factors. These factors include:
- Type of donor. A 100% HLA identical real brother or sister donor allogeneic bone marrow transplant offers the highest success rates and the lowest complication.
- The age of the patient. Children and young adults have higher success rates for allogeneic BMT for Aplastic anemia treatment in India.
- Expertise of best Aplastic anemia treatment doctor in India. The experience of the hematology and BMT specialist doctor also plays a crucial role in the outcome of Aplastic anemia treatment. CMCS Health, the global healthcare guardian for international patients is associated with the top hematologists and BMT specialist doctors in India for successful Alastic anemia treatment for international patients.
- Bone marrow transplant hospitals. The facilities at the BMT center like dedicated BMT units with separate BMT intensive care units, specially trained BMT nursing and support staff, and their synergistic care ensure the highest success rates for Aplastic anemia treatment in India.
CMCS Health has successfully coordinated allogeneic BMT for Aplastic anemia treatments by helping in the selection of the right donor and getting the treatment with the best Aplastic anemia treatment doctors in India at the top BMT centers for international patients.
Aplastic anemia treatment cost in India
Many factors influence aplastic anemia treatment costs in India. The expertise of the aplastic anemia treatment doctor, the combined experience of support and nursing staff, and their overall experience as a BMT team, type of donor and associated co-morbid factors, and any other sickness may increase the Aplastic anemia treatment cost in India. The generalized Aplastic anemia treatment cost in India is as follows:
Initial investigations for the donor and recipient of allogeneic bone marrow transplant (including HLA matching) | Aprrox. 800 - 1000 USD |
Allogeneic BMT cost for Aplastic anemia treatment in India (including 21 days BMT ICU stay for the patient, BMT infusion and stem cell collection from the donor) | Approx. 24000 - 28000 USD |
Post-successful BMT investigations cost for treatment follow-up (Blood tests, immunosuppression medication blood levels, and chimerism tests) | Approx. 500 to 800 USD |
Please Note:
- It is a generalized estimate for aplastic anemia treatment cost in India. The cost may increase on physical examination of the patient with the treating doctor.
- Any overstay in the hospital beyond the BMT package period will increase the aplastic anemia treatment cost.
- Any complication like the GVHD may also increase the cost.
Best Aplastic anemia treatment doctors in India
The best hematologists and bone marrow transplant specialist doctors performing allogeneic bone marrow transplants for curative aplastic anemia treatment in India are:
- Dr. Vikas Dua, Principal director, and pediatric hematology, Fortis Memorial Research Institute, Gurugram, India.
- Dr. Pawan Singh, Group Director, Hematology and BMT at Yatharth Hospital, Greater Noida, India.
- Dr. Rahul Bhargava, Principal Director, Hematology and BMT, Fortis Memorial Research Institute, Gurugram, India.
- Dr. Meet Kumar, Hematology and BMT specialist at Marengo Asia Hospital, Gurugram, India.
- Dr. Dharma Chaudhary, BMT and Hematology specialist at BLK MAX super specialty hospital, New Delhi, India.
- Dr. Shishir Seth, BMT and hematology specialist at Indraprastha Apollo Hospital, New Delhi, India.
- Dr. Reyaz Ahmad, BMT and Hematology specialist at Max Super Specialty Hospital, New Delhi, India.
- Dr. Gaurav Dixit, BMT and hematology specialist at Artemis Hospital, Gurugram, India.
- Dr. Satya Prakash Yadav, BMT and hematology specialist at Medanta- The Medicity, Gurugram, India.
- Dr. Shubh Prakash Sanyalm, BMT and hematology specialist at Fortis Hospital, Mulund, Mumbai, India.
Frequently asked questions about Aplastic anemia treatment in India.
The damage to bone marrow (which produces red blood cells, white blood cells, and platelets ) and its ability to produce an adequate number of blood cells are the major manifestations of Aplastic anemia. Aplastic anemia can affect a person at any age, treatment of Aplastic anemia depends on the severity and age of the patients. Children and young adults respond better to curative aplastic anemia treatment (allogeneic bone marrow transplant). Men and women are at equal risk of developing aplastic anemia but the severity of aplastic anemia is observed more in male patients. Allogeneic bone marrow transplant is a curative treatment for Aplastic anemia. The frequently asked questions about Aplastic anemia and Aplastic anemia treatment in India are:
What causes Aplastic anemia?
- Autoimmune disorders (the patient's immune system starts destroying or damaging the bone marrow or hematopoietic stem cells) so the damaged or faulty bone marrow can not produce all three types of blood cells.
- Chemotherapy or radiation therapy may also damage the bone marrow but when the treatment is over, the bone marrow may heal itself and start producing the blood cells.
- Certain antibiotics and anticonvulsants may also damage the bone marrow, ideally the bone marrow should heal once the treatment is over and start producing the blood cells.
- Inherent conditions like Fanconi anemia can be a causative factor for Aplastic anemia,
- Infection with certain viral diseases like Epstein-Barr virus, HIV, and cytomegalovirus may also cause Aplastic anemia.
- In some women during pregnancy, the immune system may have a detrimental effect on bone marrow causing Aplastic anemia.
- Exposure to certain toxic chemicals like arsenic, pesticides, certain heavy metals, and benzene may cause Aplastic anemia.
- In many cases the reasons are unknown, such cases are called idiopathic Aplastic anemia.
CMCS Health, a leading medical tourism assistance company facilitates Aplastic anemia treatment in India for international patients.
Is Aplastic anemia a dangerous disease?
Severe Aplastic anemia if not treated in time can be fatal. When not enough white blood cells are produced by the bone marrow in Aplastic anemia patients, the patient becomes prone to infections. A low number of red blood cells or hemoglobin may also affect many organs. Inadequate platelet counts expose Aplastic anemia patients to excessive bleeding due to a lack of blood clotting mechanism. Severe Aplastic anemia patients require medical treatments.
What options are there for Aplastic anemia treatments in India?
India offers curative Aplastic anemia treatment. An allogeneic bone marrow transplant is the only curative treatment option for Aplastic anemia. We offer low-cost allogeneic BMT for Aplastic anemia treatment in India. Our association with the best Aplastic anemia treatment doctors in India ensures successful Aplastic anemia treatment for international patients.
Who could be a bone marrow donor for my Aplastic anemia treatment?
The best bone marrow donor for allogeneic bone marrow transplant for the treatment of Aplastic anemia is an HLA identical real brother or sister.
Which country is better for curative Aplastic anemia (allogeneic HSCT ) treatment?
India stands out when it comes to successful yet low-cost Aplastic anemia treatment. The experience of the best BMT doctors in India, the well-trained BMT nursing and support staff, and the state-of-the-art infrastructure of top BMT centers in India clubbed with the latest cutting-edge technologies have made India the number one choice for cost-effective Aplastic anemia treatment.
What time is needed post successful BMT for a complete cure of Aplastic Anemia?
Once the bone marrow engraftment shows 100% donor chimerism the treating doctors will pronounce the bone marrow transplant for treatment of aplastic anemia successful. The blood count takes time to come up to normal level. The platelet count is the slowest to rise. Usually after one year of successful bone marrow engraftment and 100% donor chimerism, treating doctors will pronounce a complete cure for Aplastic anemia patient.
How long will be my stay in India for successful Aplastic anemia treatment?
The treatment process of an allogeneic bone marrow transplant takes place approx. one and a half to two months. A patient will be under observation for one more month after a successful BMT. In general, the patient may need to stay from 75 to 90 days for Aplastic anemia treatment in India.
Where will I stay post-discharge from the hospital after a successful Aplastic anemia treatment?
CMCS Health team will arrange a budget hotel room or a flexible rental guest house room for the stay of the patient and medical attendant in a safe and secure environment near the treatment hospital. There are many options for every need and budget for international patients for Indian stay post successful aplastic anemia treatment.
How CMCS Health will help me in my Aplastic anemia treatment in India?
Your Global healthcare guardian, CMCS Health will coordinate your aplastic anemia treatment in India with the best Aplastic anemia treatment doctors in India. CMCS Health team will empower you in selecting the best doctors and top hospitals in India for your Aplastic anemia treatment. We will also assist you in procuring a medical visa for you and your bone marrow donor and a medical-X visa for your attendants. CMCS Health's dedicated patient care experts will also assist you in your medical travel itinerary. Pickup on arrival at the airport and drop at the airport post successful Aplastic anemia treatment in India. Our dedicated expert patient care executives will schedule your appointments with the treating doctors' team and will accompany you for your OPD schedules at the treating hospital. They will also keep a close observation during your treatment and the follow-up post-successful Aplastic anemia treatment.
Will I need to come back to India for treatment follow-up?
Generally, there is no need for follow-up after successful Aplastic anemia treatment in India. Your treating doctors will ask you to do certain blood tests in your country and send the reports to us. After receiving your blood test investigation reports your dedicated patient care executive will discuss the reports with your treating doctor. Your treating doctor may tailor your immunosuppression medications depending on your reports. Your dedicated patient care expert will advise you accordingly and keep track of your progress.