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All Posts in Category: Medical treatment in India.

Best Kidney transplant hospitals in India.

Best Kidney transplant hospitals in India - CMCS Health.

Kidney transplant is needed for those patients where Kidneys have stopped working , the medical condition is called chronic renal failure or end stage renal disease. Hemodialysis is a stop gap arrangement for ESRD or CRF patients, where filtration of toxins is done through dialysis machines and erythropoietin injection are given for rise in hemoglobin and electrolyte balance is to be maintained . But Kidney transplant is permanent cure for ESRD or CRF patients. We are associated with best Indian Kidney transplant specialists at best kidney transplant hospitals in India for ESRD or CRF patients seeking Kidney transplant ( KTP ) in India.

Best Kidney transplant hospitals in India:

Max Hospital - Best cancer treatment hospital in India - CMCS Health.
Max healthcare group hospitals.

Max healthcare is one of the leading healthcare provider in India , with hospitals in major cities like Delhi , Ghaziabad , Gurgaon and Mumbai.

Max Super speciality hospital ,New Delhi , India.

Located in the heart of south Delhi, the 530+ bedded Max Super Speciality Hospital, Saket, is widely considered as one of the best kidney transplant hospitals in India. 

Max Hospital, India adopts advanced technologies for kidney transplants surgeries in India. These include:

  • Advanced ABO-incompatible kidney transplantation procedure
  • Robotic kidney transplantation surgery and  laparoscopic surgeries of the urinary tract.
  • Max Hospital is  equipped with state-of-the-art facilities and eminent nephrologists  and transplant urology surgeons,who have conducted thousands of kidney transplant surgeries.

Manipal group of hospitals

Manipal group of Hospitals.

Manipal Hospitals as an entity came into existence in 1991 with the launch of 650-bed flagship hospital at Old Airport Road, Bangalore.

Today, Manipal group of hospitals are one of India’s leading healthcare groups with over 7600 beds across 27 hospitals.

Manipal Hospital , New Delhi , India

Manipal hospital, New Delhi, has one of the best kidney transplant facilities in India. The kidney transplant team at Manipal hospitals is highly experienced and have shown excellent long term transplant outcomes. The kidney transplant team at Manipal hospitals comprises transplant nephrologists, kidney transplant surgeons, anesthesiologists and critical care experts. 

During kidney transplantation, the surgeon places a new kidney from either a deceased or living donor. The following types of kidney transplant surgery are done at Manipal hospitals:

  • Living related donor kidney transplant
  • ABO-incompatible kidney transplants 
  • Robotic kidney transplants 
  • Deceased Donor (Cadaveric)
  • Combined Liver Kidney Transplant
  • Pediatric Kidney Transplant

Medanta - The medicity

Medanta _Yhe medicity - Best Kidney transplant hospital in India - CMCS Health
Medanta - The Medicity

Medanta Institute of Kidney and Urology is a unique resource for those suffering from diseases of the urinary system, including the kidneys, bladder and prostate gland. As the major tertiary and quaternary care centre in North India, Medanta offer some of the region’s finest experts covering every major urology and nephrology speciality.

Medanta’s doctors at Kidney Transplant Clinic use proven innovations to treat people with chronic kidney disease or end-stage renal disease (ESRD). Experience in using minimally invasive surgery, new medicines to prevent organ rejection and specialised procedures makes Medanta a leader in transplant outcomes in India. Patients for renal transplantation undergo an extensive evaluation to identify factors that may have an adverse effect on the outcome. At Medanta, they have a special committee that meets regularly to discuss the results of the evaluation to identify the best treatment for the patient.

Apollo group of hospitals

Apollo group started their hospital chains in 1983 under Dr Prathap C Reddy . Over a period of time they have established bench marks among the private healthcare providers in India as a leading hospital chain with more than 7000 highly qualified doctors and high end diagnostics professionals.

Indraprastha Apollo hospital , New Delhi

The Apollo Institutes of Transplant program is one of the world’s largest and most comprehensive solid multi-organ transplantation in India .

Indraprastha Apollo Hospital - Best Kidney transplant hospitals in India _ CMCS Health.
Indraprastha Apollo Hospital , New Delhi , India.

Apollo Kidney transplant center in New Delhi , India is one of the pioneer hospitals in India to start kidney transplant in India for ESRD ( end stage renal disease ) or CRF ( chronic renal failure ) patients.

Apollo hospital , New Delhi offers services for kidney biopsies, dialysis and kidney transplantation under one roof. It is a close knit unit which includes highly specialised nephrologists, urologists and transplant surgeons

At CMCS health , we are associated with many other Kidney transplant hospitals in India , offering cost effective Kidney transplant surgery for medical travelers , seeking kidney transplant in India.

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Best BMT hospitals-doctors in India

Bone marrow transplants also called stem cell transplants are life-saving medical treatments for blood disorders and immune deficiency disorders. At CMCS Health we are associated with the Best BMT hospitals-doctors in India for providing cost-effective bone marrow transplants in India for medical travelers to India.

Best BMT hospitals-doctors in India :

Best BMT hospitals in India - Bone marrow transplant in India - CMCS Health.

All the hospital are well equipped and offer HEPA MERV filtered dedicated BMT units with stringent quality control measures for avoiding infections related to bone marrow transplant treatments.

Fortis memorial research Institute , Gurgaon , India - Best BMT hospital in India - CMCS Health.

Fortis Memorial research Institute, Gurgaon, India.

Flagship hospital for Fortis healthcare.

Fortis Memorial Research Institute (FMRI) is a multi-super-speciality, quaternary care hospital, considered as one of the best hospitals in Gurugram, India.

Institute of Blood disorders and Bone marrow transplant at Fortis memorial research institute has successfully performed more than 1000 allogenic and autologous bone marrow transplants for patients from 36 countries .

Fortis memorial research institute is having both adult and pediatric bone marrow transplant specialists and a team of total 8 highly qualified and well experienced doctors to mange every aspect of bone marrow transplants. It is one of the best bone marrow transplant hospitals in India offering HLA Identical unrelated donor bone marrow transplant ( MUD - BMT ) for thalassemia treatment in India.

Fortis memorial research institute follows stringent global standard bone marrow transplant related infection control policies.

Best bone marrow transplant doctors in India , at Fortis memorial research Institute , Gurugram:

Best BMT doctors in India - FMRI - CMCS Health.

Dr Rahul Bhargava

Dr. Rahul Bhargava is a leading hematologist BMT specialist of Delhi/Gurugram.

Pediatric BMT specialist - FMRI - CMCS Health.

Dr. Vikas Dua

Dr. Vikas Dua is a pediatric hemato-oncologist and child BMT specialist at FMRI, Gurugram.

Artemis Hospital , Gurgaon , India - Best BMT hospitals in India - CMCS Health.

Artemis Hospital,

Gurgaon, India.

The hematology department at Artemis hospital provides bone marrow transplant ( BMT ) for various blood disorders to both children and adults.

They offer treatments for various disorders like thalassemia, sickle cell anemia, pure red cell aplasia, hemolytic anemias, nutritional anemias and other anemias of various etiologies, hemoglobinopathies, Fanconi anemia and various inherited bone marrow failure disorders, ITP, hemophilia, various bleeding disorders, deep venous thrombosis, evaluation of low blood counts and various hematological malignancies.

Artemis hospital is also providing blood cancer treatments by performing allogenic bone marrow transplant for Acute myeloid leukaemia , Acute lymphoblastic leukemia for both adult and pediatric blood cancer patients.

Autologous bone marrow transplants are done for medical conditions like multiple myeloma.

Best bone marrow transplant doctors in India at Artemis Hospital , Gurugram , India.

Best Indian BMT doctors - Artemis Hospital - CMCS Health.

Dr. Pawan Kumar Singh

Dr. Pawan Kumar Singh is head of department - Hematology, and BMT at Artemis hospital.

Medanta - The medicity

Gurgaon , India.

Medanta – The Medicity is one of India’s largest multi-super specialty institutes located in Gurgaon, a bustling town in the National Capital Region. Founded by eminent cardiac surgeon, Dr. Naresh Trehan, the institution has been envisioned with the aim of bringing to India the highest standards of medical care along with clinical research, education and training. Medanta is governed under the guiding principles of providing medical services to patients with care, compassion, commitment.

There are many other BMT hospitals in India offering best and globally at par bone marrow transplant services at a very reasonable and affordable cost for medical travelers seeking bone marrow transplant in India.

Best bone marrow transplant doctors in India at Medanta - The medicity , Gurugram, India:

Dr Ashok K. Vaid - Best BMT doctor in India - CMCS Health.

Dr. Ashok K. Vaid

Dr. Ashok Kumar Vaid is Hemato-oncologist and chairman at medical and hemato-oncology institute, Medanta-the medicity, Gurugram, India.

Dr. Satya Prakash Yadav - Best BMT doctor in India - CMCS Health.

Dr. Satya Prakash Yadav

Director - Paediatric Hemato Oncology & Bone Marrow Transplant - Cancer Institute, at Medanta - The mendicity, Gurugram , India.

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Best cancer treatment hospitals in India.

Cancer treatment requires a comprehensive and complete set up with specialist doctors and supporting diagnostics facilities . At CMCS Health , we are associated with best cancer treatment hospitals in India for facilitating cancer treatments in India for global medical travelers.

Best cancer treatment hospitals in India :

Cancer treatments require a joint and close working of three streams of cancer treatment specialists , the medical oncologists , oncology (cancer ) surgeons and radiation oncologists . Best cancer hospitals in India are regularly conducting tumor board meetings for discussion on treatment protocols for every cancer patient and chalking out best effective treatment plan for every cancer patient. They are ably supported by state of art and latest diagnostic facilities including nuclear medicine for complete and comprehensive cancer treatment in India.

Best Cancer treatment hospitals for cancer treatment in India .
Best Cancer hospitals for cancer treatment in India

Fortis Healthcare group of hospitals for cancer treatment in India:

Fortis group have many hospitals in India offering complete and comprehensive cancer treatments.

Fortis Memorial research Institute , Gurugram, India:

Fortis memorial research institute is flagship hospital of Fortis group. Oncology Department at Fortis memorial research Institute comprises of dedicated medical oncology unit under the chairmanship of renowned Medical Oncology specialist Dr Vinod Raina , Hematology and blood cancer unit under Dr Rahul Bhargava , Surgical Oncology department consisting of Dr Vedant Kabra , Dr Rama Joshi etc. and Radiation Oncology under Dr. A.K.Anand.

Fortis memorial research Institute - Best cancer treatment hospitals in India - CMCS Health.

Fortis memorial research Institute also had a dedicated nuclear medicine unit and Pathology and diagnostic units for complete and comprehensive cancer treatment .

Medanta - The medicity , Gurugram , Haryana:

The Medanta Cancer Institute comprises the Division of Medical and Haemato- Oncology, Division of Radiation Oncology and multiple organ-specific surgical cancer divisions including Breast Services and Head and Neck Oncology. Highly experienced and trained oncologists work-in-coordination with the surgeons across departments and specialties to provide supreme care to the patient.

Medanta-The medicity - Best cancer treatment hospital in India - CMCS Health.

With high-end technologies such as CyberKnife VSI Robotic Radiosurgery, VMAT, IGRT, Tomotheraphy and other high end diagnostic and imaging equipment, cancer treatment specialist doctors at Medanta leave no stone unturned to make sure they are giving patients the best possible treatment available anywhere in the world.

Max Healthcare group of Hospitals :

Max Institute of Cancer Care, offers a holistic and integrated treatment by consolidating views of experts in Surgical Oncology, Radiation Oncology, and Medical Oncology. Cancer specialist doctors at Max group of hospitals located in Saket, Patparganj, Vaishali, Shalimar Bagh, Gurgaon, Max Smart, Mohali and Bathinda, specialize in treating cancers affecting Breast, Head and Neck, Lung, Gastrointestinal tract and others.

Max Hospital - Best cancer treatment hospital in India - CMCS Health.

Max healthcare hospitals provides combination of Chemotherapy, Radiation Therapy, Surgery and Targeted Therapy. They are the first facility in northern India to acquire Novalis Tx for IMRT/IGRT, Radiosurgery, HIPEC and SRS/SRT. They are equipped with an advanced Da Vinci XI Robotic System for treating complex conditions like cancers of prostate, cervix, colon/rectum, as well as heart tumors. The procedure is the next frontier for minimally invasive surgery.

Artemis Hospital , Gurugram , India:

Artemis Cancer Institute also has the the advantage of having the entire treatment modalities under one roof:

  • Medical Oncology
  • Radiation oncology
  • Surgical oncology
Artemis Hospital - Best cancer treatment hospital in India - CMCS Health.

 In addition to the above features , Artemis hospital offers following services :

  • OPD Documentation and statistics
  • Special nursing and rehabilitative services as required 
  • Pain clinic
  • Terminal care
  • Tele medicine and communication centre
  • Day care Chemo therapy centre
  • Second opinions & national and international affiliations and networking
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HIFU for prostate cancer treatment -Medical Oncology.

HIFU for prostate cancer treatment in India

HIFU ( high intensity focused ultrasound ) is a nonsurgical procedure for the treatment of prostate cancer. At CMCS Health, we offer cost-effective HIFU treatment with the best and most experienced Indian prostate cancer specialists for medical travelers, seeking prostate cancer treatment in India.

HIFU for prostate cancer treatment in India.

What is HIFU:

HIFU ( high intensity focused ultrasound ) is a novel nonsurgical procedure approved by the US FDA for the treatment of localized and non metastatic prostate cancer. In the HIFU procedure, multiple ultrasound waves are produced at a higher intensity and in a highly focused form aimed at cancerous tissues in the prostate gland.

Which patient are ideal for HIFU treatment for prostate cancer :

Those patients who have a smaller prostate gland and in whom cancer is localized and not metastatic are the best suited for HIFU treatment for prostate cancer.

HIFU can also be used as an alternative or follow-up treatment for those patients where other treatments like surgery or radiation therapy have failed and the tumor is confined to a small area of the prostate gland.

Advantages of HIFU for prostate cancer treatment :

  • It does not include surgery or radiation therapy
  • Focal HIFU can treat smaller prostate cancerous tissues without harming surrounding healthy tissues, muscles, and nerves
  • It is an outpatient ( OPD ) procedure with no hospital stay, the patient can return the home same day and start his work and other activities within 24 hours of the procedure.
  • It has fewer chances of urinary incontinence or erectile dysfunction as compared to surgery or radiation therapy

Lowest cost - Highest Quality HIFU for prostate cancer treatment in India :

The cost of HIFU treatment for prostate cancer depends on the size of tumor, hospital and experience of the treating doctor .

Best quality HIFU treatment for prostate cancer treatment in India may range from 3500 to 5000 USD .

HIFU for prostate cancer treatment in India :

At CMCS Health, we are associated with the best Indian prostate cancer specialists including Medical Oncologists who are experts in chemotherapy, immunotherapy, targeted therapy, and hormone therapy, Uro.- Onco. surgeons who are well versed with Robot-assisted prostatectomy and Radiation oncologists for complete and comprehensive prostate cancer treatment in India.

DR Vineet Govinda Gupta is a young and dynamic medical oncologist and senior consultant - Medical oncology at Artemis hospital , Gurgaon , India.

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CA Cervix- CA Ovary - CA Uterus Surgeon , cervical cancer treatment in India .

Cervical cancer treatment in India | Onco-Surgery

Cervical cancer is a cancer that usually occur in tissues of cervix , a tubule connecting vaginal opening with uterine cavity. At CMCS Health , we are associated with best Indian cervical cancer treatment specialists for cervical cancer treatment in India | Onco-Surgery , at Best Indian hospitals for cancer treatment , for global medical travelers.

Cervical cancer treatment in India - CMCS Health.

Cervical cancer usually start as abnormal changes in tissues of cervix . In majority of cases , it is Human Papillomavirus infection that is responsible for these abnormal changes. The cells which undergo these abnormal changes are called atypical cells. Some of the atypical cells go away without treatment, but others can become cancerous.

PAP smear and HPV screening for women at risk of developing cervical cancer plays an important role in early diagnosis of Cervical cancer or CA cervix.

Cervical cancer treatment in India | Onco-Surgery

Cervical cancer treatment in India depends on stage of cancer , overall health of patient and personal preference of patient( If the patient wants to bear a child in future) .

As most of the cancers , Surgery is the gold standard for early stage and localized cervical cancers.

We are offering following surgical procedures for cervical cancer treatment in India .

Conization :

Conization is surgery for excision of cervical intraepithelial neoplasia. It involves removing a cone-shaped piece of tissue from the cervix.

LEEP or LEETZ :

Leep or Leetz involve removing microinvasive cervical cancer tissues with a thin wire hook heated by electricity.

Hysterectomy:

Hysterectomy is removal of uterus along with cervix. Vagina and pelvic lymph nodes are left as well as ovaries , unless and until there is another reason to remove them.

Hysterectomy can be classified as simple hysterectomy ( removal of uterus along with cervix ) , radical hysterectomy ( removal of uterus with surrounding tissues , cervix and upper part of vagina connected to cervix and some lymph nodes ) and modified radical hysterectomy.

There are different ways for doing the hysterotomy in a patient.

  • Abdominal Hysterectomy is done through a surgical incision in the front of abdomen. Abdominal hysterectomy may require hospitalization of 3 to 4 days and complete recovery takes almost 4 to 5 weeks.
  • Vaginal hysterectomy involves removing the uterus through the vagina.
  • Laparoscopic hysterectomy is done with the help of a laparoscope and small incision or cut as compared to open hysterotomy and uterus is removed through a small cut in vagina. Both Vaginal hysterectomy and laparoscopic hysterectomy require 1 to 2 days of hospital stay and 2 to 3 weeks in complete recovery.
  • Robot assisted hysterectomy is done with the help of a robot for more precise surgery.

Bilateral salpingo oophorectomy :

Bilateral salpingo oophorectomy is a surgery involving both the ovaries along with both the Fallopian tubes.It is done along with hysterotomy.

Radical trachelectomy :

Radical trachelectomy has become an acceptable alternative to a hysterectomy for younger patients who want to bear a child in future. It involves removal of the cervix and the upper part of the vagina but not the body of the uterus , the nearby lymph nodes are also removed using laparoscopy.

After radical trachelectomy some women are able to carry a term pregnancy and deliver a healthy child through C-section.

Pelvic exenteration :

Exenteration removal of the uterus, vagina, lower colon, rectum, or bladder if cervical cancer has spread to these organs after radiation therapy . It is rarely done and not recommended but used only for those cervical cancer patients whose cancer has come back after radiation treatment.

At Fortis memorial research Institute , We offer a comprehensive treatment for cervical cancer in collaboration with Medical oncology specialists ( Chemotherapy , targeted drug therapy and immunotherapy ) and Radiation oncology specialists ( radiation therapy ).

Dr Rama Joshi - Gynecological Oncology Surgeon , is director - Gynecological Oncology at Fortis Memorial Research institute Gurgaon., India.

With more than two decades of experience of performing all radical oncology surgeries for Gynecological cancers,she is one of the leading Gynecological Oncology surgeon of North India. 

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Thalassemia treatment | BMT

Thalassemia Treatment in India | BMT

Thalassemia treatment in India | BMT

Thalassemia Treatment in India| BMT

Thalassemia is a genetic disorder which affects the hemoglobin in a patient. The conservative treatment consists of recurrent blood transfusions.These recurrent blood transfusion may cause iron overload in the patient and subsequently bone deformity,liver damage and other health complications follow. Bone marrow transplant is considered a viable treatment option for pediatrics thalassemic patients.At CMCS Health, we offer Child Thalassemia treatment In India | BMT in India ,with the best specialist Indian medical doctors at well equipped and well managed treatment centers and hospitals at an affordable and reasonable cost with very good success rates.

What is Thalassemia?

Thalassemia is a medical condition in which the affected person's body produces abnormal hemoglobin. This abnormal hemoglobin gets the excessive and premature destruction of RBCs subsequently causing anemia in the affected person. A person with thalassemia may require frequent blood transfusions depending upon type and severity. We offer comprehensive thalassemia treatment in India | BMT .

What are the causes of Thalassemia?

Thalassemia is a mutation in genes responsible for hemoglobin production. It is a genetic or hereditary disorder, which means the disease is passed on to the patient by the parents who are the carrier of the disorder.

What are the Types of Thalassemia?

Thalassemia can be broadly classified as Alpha and Beta Thalassemia. There are many subtypes of Thalassemia.

Understanding Thalassemia:

Hemoglobin molecules are made up of Alpha and Beta parts. Both Alpha and Beta parts are prone to genetic mutations.

Alpha Thalassemia :

Alpha Thalassemia is more common among the south east Asians , south china,India, Africa and middle eastern countries.

Four Genes are involved in formation of Alpha Hemoglobin chain. A child will acquire two each from both father and mother.

One mutated gene either from father or mother out of the four genes,causes either no symptoms or mild symptoms in child,the child will grow as healthy human being but will be called a silent carrier of Alpha Thalassemia.

Two mutated genes either from father or mother,the symptoms will be mild in child, such a thalassemia is called Alpha thalassemia minor.

Three mutated genes will cause moderate to severe anemia in child. The child will have chronic anemia and will require regular blood transfusions throughout his/her life.This medical condition is also referred as Hemoglobin H disease.

Mutation in all four genes is called Alpha Thalassemia major or Bart hydrops fetalis. Fetuses with mutations in all four genes do not survive or die shortly after birth. Blood transfusion given to fetus with four gene mutations rarely works and have very low success rates.

Beta Thalassemia:

Beta Thalassemia is more common among the people of Mediterranean region. The prevalence is high in North Africa and west asia. Substantial population in Maldives and certain islands in Indian ocean are the careers.

Two genes one each from the father and mother constitutes Beta hemoglobin chain.

One gene mutation causes mild symptoms and are referred as Beta Thalassemia minor.

If both the genes have mutation, the signs and symptoms may vary from moderate to severe.The affected condition is called Cooley's Anemia or Beta Thalassemia Major. Babies born with mutations in both genes are usually born as healthy child but develops complications of thalassemia within two years of birth.Another form of Beta Thalassemia with both genes mutation but with milder symptoms is called Beta Thalassemia Intermedia.

What are signs and symptoms of Thalassemia?

The signs and symptoms of thalassemia depends on it's type.

Signs and Symptoms of Alpha-Thalassemia:

Majority of children with Alpha-Thalassemia or Hemoglobin-H disease are healthy in general.Symptoms may vary from mild to moderate anemia,Fatigue,drowsiness,pale skin or jaundice,abnormally cold hand and feet ,chest pain,frequent headaches,shortness of breath, dizziness and feeling of impending being faint.enlarged spleen and possibly soft to touch and enlarged liver,they may also have deformity of bones,forehead,cheeks ans jaw may overgrow.

Signs and Symptoms of Beta Thalassemia:

Signs and symptoms of Beta Thalassemia ( thalassemia major or Cooley's anemia ) is generally severe and patient may require regular blood transfusions, the symptoms may include jaundice, frequent infections,cold hand and feet,shortness of breath,a general feeling of malice and being tired,poor appetite,skeletal deformity,delayed growth and delayed puberty,iron overload in body that can harm spleen,heart and liver.

How Thalassemia is diagnosed

Different diagnostics tests are recommended by treating doctor,if he/she suspects the patient to have Thalassemia.

  • Complete Blood Count ( CBC) is recommended for hemoglobin levels,as thalassemia patients usually have lower hemoglobin.
  • Microscopic examination: is conducted to ascertain any abnormality in RBCs,Thalassemia patients RBCs are smaller in size as compared to an unaffected person.RBCs with uneven hemoglobin distribution,that gives Bull's eye appearance under the microscope.
  • A reticulocyte Count is done to ascertain how fast RBCs are formed by the bone marrow and released in blood.
  • Hemoglobin electrophoresis separates different molecules in RBCs,allowing identification of abnormal RBCs.
  • DNA Analysis  is done to diagnose thalassemia or to ascertain if the person is carrier of mutated hemoglobin gene cells.
  • Iron tests in blood  are done to ascertain if the patient's anemia is because of thalassemia or iron deficiency,as thalassemic patient's do not have Iron deficiency.
  • Physical examination is conducted to ascertain enlarged spleen.

    Thalassemia Treatment in India|BMT

Treatment for moderate to severe thalassemia may involve frequent blood transfusions.Frequent blood transfusions may cause iron overload in patient's body which in longer run may damage spleen,heart and liver.

Iron Chelation is removal of excess iron from the blood. Patients may be prescribed subcutaneous injections of deferoxamine or oral deferasirox.

Bone Marrow or Stem Cell transplant is a better treatment option for Thalassemia. Chemotherapy cycles given to the patient prior to BMT for destroying abnormal cells and once the patient is in remission phase,bone marrow from a compatible donor preferably a sibling is transplanted in thalassemia patients.

Surgery is also done for some patient with bone deformity and sometimes surgery  removal of spleen and gall bladder is also done.

Dr Vikas Dua is consultant Pediatrics bone marrow transplant specialist at Fortis Memorial Research Institute Gurgaon,India.

Dr Vikas Dua did his advanced Fellowship in Pediatrics Bone Marrow Transplant from National University Hospital Singapore and also did his training in child BMT from world's No.1 institute in pead.BMT ,St. Jude's Children research Hospital Memphis,USA.

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Best Indian bone marrow transplant specialist | CMCS health.

Sickle cell treatment in India | BMT

What is Sickle cell disease?

Sickle cell disease treatment in India | BMT
Sickle cell disease treatment

Sickle cell anemia or sickle cell disease is common in African continent At CMCS Health , we are associated with best Indian Hematologist and BMT specialists for Sickle cell treatment in India | BMT for sickle cell disease patients seeking sickle cell disease treatment in India.

Sickle cell anemia is a severe form of anemia caused by genetic mutation in the Red blood cells. It is a genetic disorder which is inherited by the patient from the two faulty hemoglobin genes from both the parents. Because of the genetic mutation,the shape of RBC ,which is flexible circular disc shaped changes to rigid sickle or crescent shaped rods. Hemoglobin a protein in RBCs,works as a transporter of nutrients and oxygen to cells all across the body.Normal RBCs are disc shaped,with the centers partially scooped out. They are flexible and soft and therefore have the capacity to squeeze through even the tiniest of blood vessels to reach every cell in the body.Due to genetic mutation the RBCs acquire the shape of a crescent moon or Sickle and become rigid and brittle.These Abnormal shaped RBCs which are not flexible get struck in small blood vessels causing slow or blockage of blood flow to other tissues of body and disrupt supply of Oxygen to those parts. Moreover the lifespan of abnormal sickle shaped RBCs is only 10-20 days as compared to 120 days of normal RBCs.Human body keeps on forming new RBCs to replace the old ones,but in a person with sickle cell disease the balance in formation of new RBCs and Destruction of existing RBCs is disturbed. This results in lower RBC count or anemia in a person suffering with Sickle cell disease. Bone marrow transplant in India offers a viable option for Sickle cell treatment in India.

At CMCS Health , we are associated with best Indian bone marrow transplant hospitals for Sickle cell treatment in India.

What are complications of Sickle cell disease?

Sickle cell anemia may have different complications in different people at different stages of disease,but the major and severe complications for a person suffering from sickle cell anemia can be broadly classified as Acute and chronic.

Acute Complication:

Sickle cell crisis:

Sickle cell crisis or VAS ( Vaso occlusive crisis ) manifests as acute severe pain.Sickle cells disrupts blood supply through smaller capillaries resulting in ischemia. Sudden pain across body that may persist from a few hours to a few days.The pain usually occurs in limbs,chest and back.

Fever and infections:

Patients with sickle cell disease are prone to severe bacterial infections because of reduction or absence of splenic function. This may expose the patient to extremely high risk of septicemia and meningitis.Pneumonia is the most common infection ,meningitis,influenza and hepatitis are other infections occurring in sickle cell disease patients.

A Stroke:

Sickle cell disease may cause a a stroke in an affected person because of oxygen deprivation due to blockage in supply of blood to tissue of brain. Some of the sickle cell anemia patients may experience a Transient ischemic attack.

Acute Chest Syndrome:

Pneumonia like complications in a child or adult suffering from sickle cell disease. The reason could be an infection or sickle cells trapped in micro capillaries of lungs.

Hepatobiliary complications:

Hepatobiliary tract abnormalities are common in sickle cell disease patients.They may include cholelithiasis, acute cholecystitis, biliary sludge, and acute choledocholithiasis,acute Hepatic Sequestration and acute intrahepatic cholestasis.

Acute renal failure:

A decrease in kidney functions due to dehydration or obstruction or even because of intrinsic renal disease.

Acute Anemia:

May be because of Splenic sequestration.

Multisystem Organ failure:

A systemic failure of lungs,liver and kidney is a life threatening medical condition for sickle cell anemia patients.

Chronic Complications:

Vision Problems:

A sickle cell disease patient may develop vision problems over a period of time.It may include proliferative sickle retinopathy and vitreous hemorrhage. Complete vision loss is also possible.

Avascular Necrosis:

Avascular or aseptic necrosis can occur when capillaries are occluded by sickled erythrocytes at distal portions of a bone, near a joint, where hypoxia is maximal and collateral circulation is inadequate .The most common site for sickle cell anemia induced avascular necrosis is femoral neck.

Leg Ulcers:

Leg ulcers appear in patients of sickle cell anemia.

Pulmonary Hypertension:

Pulmonary hypertension occur in sickle cell disease patients.

Sickle cell treatment in India | BMT :

Sickle cell anemia patients are usually referred to a Hematologist ( A doctor who has specialized in blood disease management). Treatment of sickle cell anemia may involve determining many factors by the treating hematologist.Treatment of sickle cell anemia includes regular monitoring and follow up with a hematologist,Medications for management of symptoms and complications,pain management,blood transfusions, oxygen supplementation and allogeneic Bone Marrow transplant.

Stem cell or Bone marrow transplant is a viable treatment option for those young sickle cell anemia patients where the diseases condition is severe and can not be managed with conventional methods. A sickle cell anemia child who is having a matching sibling donor is referred for a bone marrow transplant by the hematologist considering all the pros and cons. Risk involved is big but a stem cell or bone marrow transplant is the only cure for sickle cell anemia child or young adult.

Before the transplant, bone marrow cells  are taken from a close matching healthy brother or sister. The patient with sickle cell disease is then treated with chemotherapy and radiation that destroy his or her bone marrow cells. After that, the donated bone marrow stem cells are transplanted in the patient.

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